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The Advanced Imaging for Glaucoma (AIG) project is a bioengineering partnership (NIH 1 R01 EY013516) sponsored by the National Eye Institute to improve quantitative imaging technologies for glaucoma diagnosis and management. The AIG Study Group consists of the investigators and staff in the clinical study arm of the partnership and the supporting resource centers. The clinical study was active 2005-2013.

Principal Investigator: David Huang, MD, PhD1

Steering Committee: David Huang, MD, PhD (Chair)1; Brian Francis, MD2; David S. Greenfield, MD3; Richard K. Parrish II, MD3 (2012-13); Joel S. Schuman, MD4; Rohit Varma, MD, MPH5

Clinical Centers:

Bascom Palmer Eye Institute, Palm Beach, FL

Investigators:  David S. Greenfield, MD*; Krishna S. Kishor, MD (2010-13); Carolyn D. Quinn, MD (2008-13)

Study Coordinators:  Shawn Iverson, DO (2011-13); Nayara Kish, BS, CCRC (2010-12); Jose Rebimbas, BS, CCRC (2012-13); Debra Weiss, CRC (2003-10)

Doheny Eye Institute, Los Angeles, CA

Investigators:  Brian Francis, MD*; Vikas Chopra, MD (2004-13); Rohit Varma, MD, MPH*2,5

Study Coordinators:  John Gil-Flamer, COT; Judith Linton, COA (2010-13); Sylvia Ramos, CCRP (2004-10)


UPMC Eye Center, Pittsburgh, PA

Investigators: Joel S. Schuman, MD*; Eiyass Albeiruti, MD (2009-13); Nils Loewen, MD (2012-13); Robert Noecker, MD (2005-2010)

Study Coordinators: Michael DeRosa, BS, BA (2012-13); Greg Owens, BA, CCRP (2010-13); Melessa Salay, BA (2010-13); Kristy Truman, COA (2010-13)

*Site principal investigator

Resource Centers:

Coordinating Center

David Huang, MD, PhD (Director); Janice Ladwig, COT, CCRP (2012-13), Michelle Montalto, BS (2010-12); Sylvia Ramos, CCRP (2004-10)

Advanced Imaging Analysis

Hiroshi Ishikawa, MD4; Larry Kagemann, MS4 (2003-10); Mitra Sehi, PhD3; Ou Tan, PhD1; Yimin Wang, PhD1 (2006-12); Gadi Wollstein, MD4


Sharon Bi6, MCIS (2006-13); Swati Chakraborty, MS (2003-09); Robert DiLaura, MBA, DBA6 (2009-12); Bo Hu, PhD6 (2012-13); John Sell (2003-06)

Disc Reading Center (2012-13)

Richard K. Parrish II, MD (Director); Eleonore Savatovsky, PhD


Doppler OCT Reading Center (2009-13)

Srinivas R. Sadda, MD (Director); Ranjith Konduru, MD (2009-12); Elnaz Rakhshan, MD (2011-12); Sowmya Srinivas, MBBS (2011-13)



Ake T.H. Lu, PhD (2004-09); Xinbo Zhang, PhD1 (2009-13)


  1. Casey Eye Institute, Oregon Health & Science University, Portland, OR

  2. Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, CA

  3. Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL

  4. UPMC Eye Center, University of Pittsburgh Medical Center, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA

  5. University of Illinois-Chicago, Chicago, IL (after 2012)

  6. Cleveland Clinic, Cleveland, OH


Financial Interest Statements

Dr. Chopra received honoraria from Optovue. Dr. Greenfield receives research support from Optovue, Carl Zeiss, and Heidelberg. Drs. Huang and Schuman receive royalties for an optical coherence tomography patent owned and licensed by the Massachusetts Institute of Technology and Massachusetts Eye & Ear Infirmary to Carl Zeiss Meditec, Inc. Drs. Huang, Tan and Wang have a financial interest in Optovue, a company involved in the study.  The nature of this financial interest and the design of the study have been reviewed by a committee at OHSU and a plan has been put into place to ensure this research study is not affected by the financial interest.  Dr. Sadda has served as a consultant for Optos, and Carl Zeiss Meditec, and has received research support from Optovue, Optos, and Carl Zeiss Meditec. Dr. Varma received research grants, honoraria and/or travel support from Carl Zeiss Meditec, Heidelberg Engineering and Optovue.


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